Pr. Isaac Chiu - Nociceptor neurons in host defense and barrier immunity

Séminaire de prestige organisé par les doctorants d'INFINITy
Séminaire financé par la SFR-B2S
Voici un extrait des principales publications du Pr. Isaac CHIU.
1. Bacteria activate sensory neurons that modulate pain and inflammation. Nature 501 (7465), 52-57 (2013).
2. Blocking neuronal signaling to immune cells treats streptococcal invasive infection. Cell 173 (5), 1083-1097. e22 (2018).
3. Gut-innervating nociceptor neurons regulate Peyer’s patch microfold cells and SFB levels to mediate Salmonella host defense. Cell 180 (1), 33-49. e22 (2020).
4. Neuro-immune interactions in the tissues. Immunity 52 (3), 464-474 (2020).
5. Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection. Cell 185 (22), 4190-4205. e25 (2022).