A journey into innate immune sensors: From discovery to therapy

Regulation of NLRP3 activation in CAPS

Pr. Fabio Martinon
University of Lausanne, Switzerland

NLRP3 is a thermosensor that is negatively regulated by high temperature

Dr. Rebecca Coll
Queen’s University, Belfast, UK

CAPS associated NLRP3 variants form a constitutively active inflammasome

Pr. Pablo Pelegrin
Universidad de Murcia, Spain

Spatio-temporal dynamics of ADP-heptose sensing during bacterial infection

Dr. Cécile Arrieumerlou
Institut Cochin, Paris, France